Klerimed 500mg Film-Coated Tablets - 10 Tablets

Directions:

Do not take Klerimed if you:

• are allergic to clarithromycin, other macrolide antibiotics such as erythromycin or azithromycin,
• or any of the other ingredients of this medicine (listed in section 6).
• are taking medicines called ergot alkaloids, for example ergotamine or dihydroergotamine tablets
• or use ergotamine inhalers for migraine. Consult your doctor for advice on alternative medicines.
• are taking medicines called simvastatin or lovastatin (used to lower increased blood fats such as
• cholesterol and triglycerides).
• are taking medicines called terfenadine or astemizole (for hay fever or allergies) or cisapride or
• pimozide tablets as combining these drugs can sometimes cause serious disturbances in heart
• rhythm. Consult your doctor for advice on alternative medicines.
• are taking other medicines which are known to cause serious disturbances in heart rhythm.
• are taking medicines called ticagrelor or ranolazine (for angina or to reduce the chance of heart
• attack or stroke)
• are taking a medicine called colchicine.
• have abnormally low levels of potassium or magnesium in your blood (hypokalaemia or
• hypomagnesaemia).
• are taking oral midazolam (for epilepsy).
• are taking a medicine containing lomitapide.
• have any liver and/or kidney problems.
• or someone in your family has a history of heart rhythm disorders (ventricular cardiac arrhythmia,
• including torsades de pointes) or abnormality of electrocardiogram (ECG, electrical recording of the heart) called “long QT syndrome”.

Klerimed is not suitable for use in children under 12 years of age.

Warnings and precautions

Talk to your doctor before taking Klerimed:

• if you have heart problems.
• if you are pregnant or breast feeding.
• if you need to have intravenous midazolam.
• If any of these apply to you, consult your doctor before taking Klerimed tablets.
• If you develop severe or prolonged diarrhoea during or after receiving Klerimed tablets, tell your
• doctor immediately, as this could be a symptom of more serious conditions such as
• pseudomembranous colitis or clostridium difficile-associated diarrhoea.
• PILclaritabs3.4-MT

If you develop any symptoms of liver dysfunction such as anorexia (loss of appetite), yellowing of the

skin or whites of the eyes, dark urine, itching or tender abdomen, stop taking Klerimed tablets and tell

your doctor immediately.

Long term use of Klerimed tablets may lead to infection with resistant bacteria and fungi.